GCSE option help/advice....?

I'd say do Triple Science if there's any chance of you taking one of the sciences beyond GCSE, because Applied Science isn't enough. If you're really bad at science, then I'd go for Applied (my school offers Double Award which is in between - are you sure that your school doesn't offer this?) French would also be helpful (it's always helpful doing a language until at least GCSE), and then either Art or Geography. I'm doing Art at the moment, and I can tell you from experience that if you want to get at least a B, you have to do A LOT of work for it, inside and outside of school. I wouldn't recommend Business Studies though, because you can do it for A Level without needing any prior knowledge of the subject.